MICHAEL BALLARD
mballard@uchicago.edu

Lab: Dr. Harriet de Wit

Selected Publications:

White DA, Ballard ME, Harmon AC, Holtzmam SG. Acute delta- and kappa-opioid agonist pretreatment potentiates opioid antagonist-induced suppression of water comsumption. Brain Res Bull. 2008 Aug 15;76 (6):597-604. Paper

Zhang M, Ballard ME, Unger LV, Haupt A, Gross G, Decker MW, Drescher KU, Rueter LE (2007) Effects of Antipsychotics and Selective D3 Antagonists on PPI Deficits Induced by PD 128907 and Apomorphine. Behavioral Brain Research 182(1):1-11. Paper

Ballard ME, Basso AM, Gallagher KB, Browman KE, Fox GB, Drescher KU, Gross G, Decker MW, Rueter LE, Zhang M (2007) The Drug-Induced Helplessness Test: An Animal Assay for Assessing Behavioral Despair in Response to Neuroleptic Treatment. Psychopharmacology (Berl) 190(1):1-11. Paper

Zhang M, Ballard ME, Kohlhaas KL, Browman KE, Jongen-Relo AL, Unger LV, Fox GB, Gross G, Decker MW, Drescher KU, Rueter LE (2006) Effect of Dopamine D3 Antagonists on PPI in DBA/2J Mice or PPI Deficit Induced by Neonatal Ventral Hippocampal Lesion in Rats. Neuropsychopharmacology 31(7):1382-92. Paper

Fox GB, Esbenshade TA, Pan JB, Browman KE, Zhang M, Ballard ME, Radek RJ, Miner H, Bitner RS, Krueger KM, Yao BB, Faghih R, Rueter LE, Komater VA, Drescher KU, Buckley MJ, Sullivan JP, Cowart MD, Decker MW, Hancock AA (2005) Selective H3 Receptor (H3R) Blockade: Broad Efficacy in Cognition and Schizophrenia. Inflammation Research 54 Suppl 1: S23-4. Paper

Zhang M, Ballard ME, Pan LP, Roberts S, Pu YM, Pease J, Curtis M, Cowart M, Esbenshade TA, Fox GB, Decker MW, Hancock AA, Rueter LE (2005) Lack of Cataleptogenic Potentiation with Non-Imidazole H3 Receptor Antagonist Reveals Potential Drug-Drug Interactions Between Imidazole-Based H3 Receptor Antagonists and Antipsychotic Drugs. Brain Research 1045(1-2):142-9. Paper

Fox GB, Esbenshade TA, Pan JB, Radek RJ, Krueger KM, Yao BB, Browman KE, Buckley MJ, Ballard ME, Komater VA, Miner H, Zhang M, Faghih R, Rueter LE, Bitner RS, Drescher KU, Wetter J, Marsh K, Lemaire M, Porsolt RD, Bennani YL, Sullivan JP, Cowart MD, Decker MW, Hancock AA (2005) Pharmacological properties of ABT-239 [4-(2-{2-[(2R)-2-Methylpyrrolidinyl]ethyl}-benzofuran-5-yl)benzonitrile]: II. Neurophysiological characterization and broad preclinical efficacy in cognition and schizophrenia of a potent and selective histamine H3 receptor antagonist. Journal of Pharmacology and Experimental Therapeutics 313 (1):176-90. Paper

Rueter LE, Ballard ME, Gallagher KB, Basso AM, Curzon P, Kohlhaas KL (2004) Chronic Low Dose Risperidone and Clozapine Alleviate Positive but not Negative Symptoms in the Rat Neonatal Ventral Hippocampal Lesion Model of Schizophrenia. Psychopharmacology (Berl) 176(3-4):312-9. Paper

Selected Abstracts/Presentations:

Ballard ME, Gallo DA, Bedi G, de Wit H. Effects of Acute delta-9-THC on Perception and Memory in Healthy Volunteers - Relation to Valence. Poster: National SFN Annual Meeting 2009, Chicago, Illinois, Oct. 17-21.

Ballard ME, Gallo DA, Bedi G, de Wit H. Effects of Acute delta-9-THC on Perception and Memory in Healthy Volunteers - Relation to Valence, Mood. Poster: American Psychological Association Annual Convention 2009, Toronto, Canada, Aug. 6-9.

Ballard ME, Gallo DA, Bedi G, de Wit H. Effects of Acute delta-9-THC on Perception and Memory in Healthy Volunteers - Relation to Valence, Mood. Poster: Annual Symposium of the International Cannabinoid Research Society 2009, St. Charles, Illinois, July 7-11.

Ballard ME, Zhang M, Kohlhaas KL, Browman KE, Jongen-Relo A, Unger LV, Fox GB, Gross G, Decker MW, Drescher, KU, Rueter LE. Effect of Dopamine D3 Antagonists on PPI Deficits, Naturally Occurring in DBA/2J Mice or Induced by Neonatal Ventral Hippocampal Lesions in Rats. Poster: Great Lakes Chapter ASPET Annual Meeting 2005, Downers Grove, Illinois, June 17.

Gross G, Drescher KU, Haupt A, Teschendorf HJ, Jongen-Relo A, Wicke K, Zhang M, Browman KE, Ballard ME, Rueter LE, Decker MW, Schoemaker H, Sullivan JP. ABT-127, a new selective dopamine D3 receptor antagonist: behavioral pharmacology studies. Poster: Great Lakes Chapter ASPET Annual Meeting 2005, Downers Grove, Illinois, June 17.

Ballard ME, Zhang M, Drescher KU, Gross G, Decker MW, Rueter LE. Sucrose Consumption and Drug-Induced Helplessness Tests: Preclinical Animal Models for Assessing Drug-Induced Anhedonia and Motivational Deficit. Poster: National SFN Annual Meeting 2003, New Orleans, Louisiana, Nov. 8-12.

Zhang M, Ballard ME, Drescher KU, Gross G, Decker MW, Rueter LE. Evaluation of D3 Receptor Involvement in Psychosis: Studies in Preclinical Animal Models. Poster:  National SFN Annual Meeting 2003, New Orleans, Louisiana, Nov. 8-12.

Rueter LE, Kohlhaas KL, Ballard ME, Gallagher KB, Basso AM, Curzon P. Effect of Chronic Low Dose Clozapine and Risperidone on Positive and Negative Symptoms in the Neonatal Ventral Hippocampal (VH) Lesion Model of Schizophrenia. Poster: National SFN Annual Meeting 2003, New Orleans, Louisiana, Nov. 8-12.

White DA, Ballard ME, Holtzman SG. Acute Pretreatment with Kappa-Opioid Agonists Potentiates Naltrexone-Induced Drinking Suppression in Water-Deprived Rats. Poster: National SFN Annual Meeting 2001, San Diego, California, Nov. 10-15.